VCAM1 anticorps
Aperçu rapide pour VCAM1 anticorps (ABIN6297708)
Antigène
Voir toutes VCAM1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Mouse anti-Human VCAM-1 Antibody [Sodium Azide Free]
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Specificité
- Cytoplasmic, membrane
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Purification
- Stimulated human umbilical vein endothelial cells (HUVEC) were used as the immunogen for the VCAM-1 antibody.
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Immunogène
- Stimulated human umbilical vein endothelial cells (HUVEC) were used as the immunogen for the VCAM-1 antibody.
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Indications d'application
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
Restrictions
- For Research Use only
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Buffer
- In 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
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Autre désignation
- Vascular cell adhesion protein 1
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Sujet
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Target Description: Recognizes a protein of 110 kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1), L1CAM and INCAM-100). It is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. VCAM-1 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses.
Gene Symbol: VCAM1
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ID gène
- 7412
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UniProt
- P19320
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Pathways
- Carbohydrate Homeostasis
Antigène
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